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Palaeoenvironmental evidence indicative of former climatic conditions in the Eastern and adjoining Western Cape during the last ~ 45 000 yr is presented and summarised. Interstadial conditions began before 43 000 BP but were succeeded by stadial conditions at ~ 24 000 BP. These climatic phases are designated the Birnam Interstadial and the Bottelnek Stadial after the type sites at which they were identified in the Eastern Cape. The Bottelnek Stadial apparently equates with the Last Glacial Maximum. Late Glacial warming was apparent by 18/17 000 BP. Sea level rose markedly by ~ 14 000 BP. Climatic oscillations marked the end of the Late Glacial. The Early Holocene was drier than the Late Holocene and, at least in the Drakensberg, there was marked aridity in the mid-Holocene. Human responses to these climatic events are briefly described.