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Toxic Extracts in Ponderosa Pine Needles that Produce Abortion in Mice
Author
Cogswell, C.
Kamstra, L. D.
Publisher
Society for Range Management
Publication Year
1980-01-01
Body

A reliable method to measure presence and quantity of the toxic factor in needles of ponderosa pine (Pinus ponderosa Laws.) was developed using embryo implantation and gestation in laboratory mice as the basis of the assay. The abortiofacient factor was present in both aqueous and acetone extracts of ponderosa pine needles. Control animals had significantly (P<0.1) greater number of viable embryos at 124, 148, and 172 hr post-coitum than mice fed pine needle extracts. A gestation study verified results from the implantation experiment, as few mice fed pine needle extracts delivered normal litters. Frequently, mice receiving the concentrated aqueous extract had diarrhea and decreased feed intake. Failure of implantation by 124 hr postcoitum in bred mice fed aqueous or acetone extracts of ponderosa pine can be used as an index of the risk involved in grazing ponderosa pine ranges, but cannot be used to predict losses. This material was digitized as part of a cooperative project between the Society for Range Management and the University of Arizona Libraries. The Journal of Range Management archives are made available by the Society for Range Management and the University of Arizona Libraries. Contact lbry-journals@email.arizona.edu for further information. Migrated from OJS platform August 2020

Language
en
Resource Type
Text
Document Type
Journal Issue/Article
Digital Object Identifier (DOI)
10.2307/3898227
Additional Information
Cogswell, C., & Kamstra, L. D. (1980). Toxic extracts in ponderosa pine needles that produce abortion in mice. Journal of Range Management, 33(1), 46-48.
ISSN
0022-409X
OAI Identifier
oai:repository.arizona.edu:10150/646592
Journal Volume
33
Journal Number
1
Journal Pages
46-48
Collection
Rangeland Ecology & Management (REM)
Journal Name
Journal of Range Management