Rangeland Ecology & Management

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Effects of carbachol administration in cattle grazing tall larkspur-infested range
Author
Pfister, J. A.
Manners, G. D.
Publisher
Society for Range Management
Publication Year
1995-07-01
Body

Tall larkspur (Delphinium barbeyi L. Huth.) toxicosis of cattle is a serious problem on western USA mountain rangelands. Manipulating the ruminal environment may decrease the susceptibility of cattle to larkspur intoxication. The cholinergic drug carbachol can greatly increase salivary flow and fluid passage rate in ruminants. Our objectives were to: (1) determine if chronic administration of carbachol altered ruminal fluid passage rate, ruminal pH, or water intake in grazing cattle, and (2) evaluate mineral salt supplementation as a prophylactic procedure for cattle grazing larkspur-infested rangelands. The study was conducted during summer of 1990 and 1991 near Yampa, Colo. Twelve heifers were divided randomly into 3 treatment groups: (1) carbachol administered at 0.01 mg kg-1 day-1 via subcutaneous osmotic minipumps; (2) mineral-salt supplement dosed intraruminally at 0.25 g kg-1 day-1; and (3) controls. Administration of carbachol either had no effect or a negative effect on ruminal fluid passage rate, ruminal pH, saliva production, and water intake compared with the controls. Carbachol had few consistent effects on serum electrolyte concentrations compared to the controls. Treatments did not influence cattle diet selection; cattle ate no larkspur during 1990, but selected larkspur for 16% of their diets during August, 1991. There was no indication that supplementation with mineral salt would attenuate larkspur toxicosis through increased dilution rates, or decreased larkspur consumption. Our results indicate that neither carbachol nor mineral supplementation will reduce animal susceptibility to larkspur toxicosis. The Journal of Range Management archives are made available by the Society for Range Management and the University of Arizona Libraries. Contact lbry-journals@email.arizona.edu for further information. Migrated from OJS platform August 2020

Language
en
Resource Type
Text
Document Type
Journal Issue/Article
Digital Object Identifier (DOI)
10.2307/4002487
Additional Information
Pfister, J. A., & Manners, G. D. (1995). Effects of carbachol administration in cattle grazing tall larkspur-infested range. Journal of Range Management, 48(4), 343-349.
IISN
0022-409X
OAI Identifier
oai:repository.arizona.edu:10150/644386
Journal Volume
48
Journal Number
4
Journal Pages
343-349
Journal Name
Journal of Range Management
Keywords
rumen fluids
saliva
poisoning
carbachol
electrolytes
mineral content
water intake
Delphinium barbeyi
blood serum
dietary mineral supplements
transit time
cattle
grazing
Colorado
forage